Package: ruv
Title: Detect and Remove Unwanted Variation using Negative Controls
Description: Implements the 'RUV' (Remove Unwanted Variation) algorithms.  These algorithms attempt to adjust for systematic errors of unknown origin in high-dimensional data.  The algorithms were originally developed for use with genomic data, especially microarray data, but may be useful with other types of high-dimensional data as well.  These algorithms were proposed in Gagnon-Bartsch and Speed (2012) <doi:10.1093/nar/gkz433>, Gagnon-Bartsch, Jacob and Speed (2013), and Molania, et. al. (2019) <doi:10.1093/nar/gkz433>.  The algorithms require the user to specify a set of negative control variables, as described in the references.  The algorithms included in this package are 'RUV-2', 'RUV-4', 'RUV-inv', 'RUV-rinv', 'RUV-I', and RUV-III', along with various supporting algorithms.  
Version: 0.9.7.1
Date: 2019-08-30
Imports: stats, ggplot2, scales, gridExtra
Suggests: shiny, colourpicker
Author: Johann Gagnon-Bartsch <johanngb@umich.edu> 
Maintainer: Johann Gagnon-Bartsch <johanngb@umich.edu>
License: GPL
URL: http://www-personal.umich.edu/~johanngb/ruv/
LazyLoad: yes
NeedsCompilation: yes
Packaged: 2019-08-30 20:08:45 UTC; johanngb
Repository: CRAN
Date/Publication: 2019-08-30 21:50:02 UTC
Built: R 4.4.0; aarch64-apple-darwin22.6.0; 2024-05-04 18:44:09 UTC; unix
