test_KEGG
Testing Bio.KEGG.Enzyme on enzyme.sample


ENTRY       EC 1.1.1.1
NAME        Alcohol dehydrogenase
            Aldehyde reductase
CLASS       Oxidoreductases
            Acting on the CH-OH group of donors
            With NAD+ or NADP+ as acceptor
SYSNAME     Alcohol:NAD+ oxidoreductase
REACTION    Alcohol + NAD+ = Aldehyde or Ketone + NADH
SUBSTRATE   NAD+
            Primary alcohol
            Secondary alcohol
            Cyclic secondary alcohol
            Hemiacetal
PRODUCT     Aldehyde
            Ketone
            NADH
COFACTOR    Zinc
COMMENT     A zinc protein. Acts on primary or secondary alcohols or
            hemiacetals; the animal, but not the yeast, enzyme acts also on
            cyclic secondary alcohols
            The insect enzyme is a member of the nonmetallo-short-chain
            alcohol dehydrogenase (ADH) family (Proc.Natl.Acad.Sci.USA(1991)
            88, 10064-10068).
PATHWAY     PATH: MAP00010  Glycolysis / Gluconeogenesis
            PATH: MAP00071  Fatty acid metabolism
            PATH: MAP00120  Bile acid biosynthesis
            PATH: MAP00350  Tyrosine metabolism
            PATH: MAP00561  Glycerolipid metabolism
GENES       ECO: b0356 b1241 b1478 b3589
            ECE: Z0456 Z2016 Z2232 Z5010
            ECS: ECs0411 ECs1741 ECs2082 ECs4466
            HIN: HI0185
            XFA: XF1746 XF2389
            VCH: VC1147 VC2033
            PAE: PA2119 PA2158 PA2188 PA3629 PA5427
            PMU: PM1453
            NME: NMB0546 NMB1304
            NMA: NMA0725 NMA1518
            MLO: mlr0872 mlr1136 mlr1178
            CCR: CC2516 CC3029
            BSU: BS2776 BS3211
            BHA: BH1829
            LLA: L13145 L55758
            SPY: SPy0044
            MTU: Rv0761c Rv1862 Rv2259
            MLE: ML1784 ML2053
            SYN: sll0990
            AAE: aq_1240 aq_1362
            TMA: TM0111 TM0920
            AFU: AF0024 AF0339 AF2019 AF2101
            HAL: VNG1821G
            TAC: Ta0832 Ta0833 Ta0841
            TVO: TVG0387048 TVG0995648 TVG1348694
            PHO: PH0743
            PAB: PAB1511
            APE: APE1245 APE1557 APE1963 APE2239
            SSO: SSO0472 SSO0764 SSO1220 SSO1300 SSO1646 SSO2334 SSO2441
                 SSO2494 SSO2501 SSO2536 SSO2717 SSO2800 SSO2878
            SCE: YBR145W YDL168W YGL256W YMR083W YMR303C YOL086C
            SPO: ADH1 SPAC5H10.06C SPCC13B11.04C
            ATH: At1g77120
            CEL: K12G11.3 K12G11.4
            DME: CG3425 CG3481 CG6598
            MMU: 1098256 87921 87926 87929
            HSA: 124 125 126 127 128 130 131
DISEASE     MIM: 103700  Alcohol dehydrogenase (class I), alpha polypeptide
            MIM: 103720  Alcohol dehydrogenase (class I), beta polypeptide
            MIM: 103730  Alcohol dehydrogenase (class I), gamma polypeptide
            MIM: 103740  Alcohol dehydrogenase (class II), pi polypeptide
            MIM: 600086  Alcohol dehydrogenase-7
STRUCTURES  PDB: 1A4U  1A71  1A72  1ADB  1ADC  1ADF  1ADG  1AGN  1AXE  1AXG  
                 1B14  1B15  1B16  1B2L  1BTO  1CDO  1D1S  1D1T  1DDA  1DEH  
                 1E3E  1E3I  1E3L  1EE2  1HDX  1HDY  1HDZ  1HET  1HEU  1HF3  
                 1HLD  1HSO  1HSZ  1HT0  1HTB  1LDE  1LDY  1QLH  1QLJ  1TEH  
                 2OHX  2OXI  3BTO  3HUD  5ADH  6ADH  7ADH  
DBLINKS     IUBMB Enzyme Nomenclature: 1.1.1.1
            ExPASy - ENZYME nomenclature database: 1.1.1.1
            WIT (What Is There) Metabolic Reconstruction: 1.1.1.1
            BRENDA, the Enzyme Database: 1.1.1.1
            SCOP (Structural Classification of Proteins): 1.1.1.1
///
ENTRY       EC 1.1.1.62
NAME        Estradiol 17beta-dehydrogenase
CLASS       Oxidoreductases
            Acting on the CH-OH group of donors
            With NAD+ or NADP+ as acceptor
SYSNAME     Estradiol-17beta:NAD(P)+ 17-oxidoreductase
REACTION    Estradiol-17beta + NAD+ or NADP+ = Estrone + NADH or NADPH
SUBSTRATE   Estradiol-17beta
            (S)-20-Hydroxypregn-4-en-3-one
            NAD+
            NADP+
PRODUCT     Estrone
            (S)-Pregn-4-en-3,20-dione
            NADH
            NADPH
COMMENT     Also acts on (S)-20-hydroxypregn-4-en-3-one and related
            compounds, oxidizing the (S)-20-group. B-specific with respect
            to NAD(P)+ (cf. EC 1.1.1.149).
PATHWAY     PATH: MAP00150  Androgen and estrogen metabolism
GENES       CEL: F11A5.12
            DME: CG1444 CG3415
            HSA: 3292 3293 3294 3295 3296 51478
DISEASE     MIM: 109685  Hydroxysteroid (17-beta) dehydrogenase 2
            MIM: 264300  Hydroxysteroid (17-beta) dehydrogenase 3
STRUCTURES  PDB: 1FDT  1FDS  1FDV  1FDW  1IOL  3DHE  1EQU  1DHT  1BHS  1A27  
                 1FDU  
DBLINKS     IUBMB Enzyme Nomenclature: 1.1.1.62
            ExPASy - ENZYME nomenclature database: 1.1.1.62
            WIT (What Is There) Metabolic Reconstruction: 1.1.1.62
            BRENDA, the Enzyme Database: 1.1.1.62
            SCOP (Structural Classification of Proteins): 1.1.1.62
///
ENTRY       EC 1.1.1.68
NAME        Transferred to EC 1.7.99.5
CLASS       Oxidoreductases
            Acting on the CH-OH group of donors
            With NAD+ or NADP+ as acceptor
COMMENT     Transferred entry. Now EC 1.7.99.5 -
            5,10-Methylenetetrahydrofolate reductase (FADH2).
DBLINKS     IUBMB Enzyme Nomenclature: 1.1.1.68
            ExPASy - ENZYME nomenclature database: 1.1.1.68
            WIT (What Is There) Metabolic Reconstruction: 1.1.1.68
///
ENTRY       EC 1.6.5.3
NAME        NADH dehydrogenase (ubiquinone)
            Ubiquinone reductase
            Type I dehydrogenase
            Complex I dehydrogenase
CLASS       Oxidoreductases
            Acting on NADH or NADPH
            With quinone or related compound as acceptor
SYSNAME     NADH:ubiquinone oxidoreductase
REACTION    NADH + Ubiquinone = NAD+ + Ubiquinol
SUBSTRATE   NADH
            Ubiquinone
PRODUCT     NAD+
            Ubiquinol
COFACTOR    FAD
            Iron
            Sulfur
COMMENT     A flavoprotein (FAD) containing iron-sulfur contres. The complex,
            present in mitochondria, can be degraded to form EC 1.6.99.3.
PATHWAY     PATH: MAP00130  Ubiquinone biosynthesis
            PATH: MAP00190  Oxidative phosphorylation
GENES       ECO: b2276 b2277 b2278 b2279 b2280 b2281 b2282 b2283 b2284 b2285
                 b2286 b2287 b2288
            ECE: Z3534 Z3536 Z3537 Z3538 Z3539 Z3540 Z3541 Z3542 Z3543 Z3544
                 Z3545 Z3546 Z3547
            ECS: ECs3160 ECs3161 ECs3162 ECs3163 ECs3164 ECs3165 ECs3166
                 ECs3167 ECs3168 ECs3169 ECs3170 ECs3171 ECs3172
            XFA: XF0305 XF0306 XF0307 XF0308 XF0309 XF0310 XF0311 XF0312 XF0313
                 XF0314 XF0315 XF0316 XF0317 XF0318
            VCH: VC1581 VCA0155 VCA0157
            PAE: PA1054 PA1056 PA1883 PA2637 PA2638 PA2639 PA2640 PA2641 PA2642
                 PA2643 PA2644 PA2645 PA2646 PA2647 PA2648 PA2649
            BUC: BU154 BU155 BU156 BU157 BU158 BU159 BU160 BU161 BU162 BU163
                 BU164 BU165 BU166
            NME: NMB0241 NMB0242 NMB0243 NMB0244 NMB0245 NMB0246 NMB0249
                 NMB0250 NMB0251 NMB0253 NMB0254 NMB0257 NMB0258 NMB0259
            NMA: NMA0002 NMA0005 NMA0006 NMA0008 NMA0009 NMA0010 NMA0014
                 NMA0015 NMA0016 NMA0017 NMA0018 NMA0019 NMA0747 NMA2228 NMA2229
            HPY: HP1260 HP1261 HP1262 HP1263 HP1264 HP1265 HP1266 HP1267 HP1268
                 HP1269 HP1270 HP1271 HP1272 HP1273
            HPJ: jhp1181 jhp1182 jhp1183 jhp1184 jhp1185 jhp1186 jhp1187
                 jhp1188 jhp1189 jhp1190 jhp1191 jhp1192 jhp1193 jhp1194
            CJE: Cj1566c Cj1567c Cj1568c Cj1569c Cj1570c Cj1571c Cj1572c
                 Cj1573c Cj1574c Cj1575c Cj1576c Cj1577c Cj1578c Cj1579c
            RPR: RP115 RP282 RP283 RP284 RP353 RP354 RP355 RP356 RP357 RP537
                 RP790 RP791 RP792 RP793 RP795 RP796 RP797
            MLO: mll1352 mll1354 mll1355 mll1357 mll1358 mll1359 mll1361
                 mll1362 mll1364 mll1365 mll1366 mll1367 mll1369 mll1371
                 mll1372 mll5193 mll5397 mll5398
            CCR: CC1937 CC1938 CC1939 CC1940 CC1941 CC1942 CC1945 CC1946 CC1947
                 CC1950 CC1952 CC1954 CC1955 CC1956
            BSU: BS0231
            MTU: Rv3145 Rv3146 Rv3147 Rv3148 Rv3149 Rv3150 Rv3151 Rv3152 Rv3153
                 Rv3154 Rv3155 Rv3156 Rv3157 Rv3158
            SYN: sll0026 sll0027 sll0223 sll0519 sll0520 sll0521 sll0522
                 sll1220 sll1221 sll1223 sll1732 sll1733 slr0261 slr0331
                 slr0844 slr1279 slr1280 slr1281 slr1291 slr2007 slr2009
            DRA: DR0880 DR1492 DR1493 DR1494 DR1495 DR1496 DR1497 DR1498 DR1499
                 DR1500 DR1501 DR1503 DR1504 DR1505 DR1506
            AAE: aq_1310 aq_1312 aq_1314 aq_1315 aq_1317 aq_1318 aq_1319
                 aq_1320 aq_1321 aq_1322 aq_135 aq_1373 aq_1374 aq_1375 aq_1377
                 aq_1378 aq_1379 aq_1382 aq_1383 aq_1385 aq_437 aq_551 aq_573
                 aq_574 aq_866
            TMA: TM0010 TM0011 TM0012 TM0201 TM0228 TM1105 TM1211 TM1212 TM1213
                 TM1214 TM1215 TM1216 TM1424 TM1425 TM1426
            MJA: MJ0520 MJ1309 MJ1362
            MTH: MTH1237 MTH1246 MTH1548 MTH1549 MTH393
            AFU: AF1823 AF1824 AF1825 AF1826 AF1827 AF1828 AF1829 AF1830 AF1831
            HAL: VNG0635G VNG0636G VNG0637G VNG0639G VNG0640G VNG0641C VNG0643G
                 VNG0646G VNG0647G VNG0648G
            TAC: Ta0959 Ta0960 Ta0961 Ta0962 Ta0964 Ta0965 Ta0966 Ta0967 Ta0968
                 Ta0969 Ta0970
            TVO: TVG1157047 TVG1158465 TVG1160017 TVG1161017 TVG1162018
                 TVG1162541 TVG1162786 TVG1163214 TVG1164251 TVG1165354
                 TVG1165809 TVG1166270
            PHO: PH0941 PH0942 PH1431 PH1446 PH1447 PH1448 PH1449 PH1450 PH1451
                 PH1452 PH1453
            PAB: PAB0488 PAB0490 PAB0492 PAB0493 PAB0494 PAB0495 PAB0496
                 PAB0805 PAB0806 PAB1888 PAB2416
            APE: APE1410 APE1411 APE1415 APE1417 APE1418 APE1419 APE1421
                 APE1422 APE1426 APE1428 APE1430
            SSO: SSO0322 SSO0323 SSO0324 SSO0325 SSO0326 SSO0327 SSO0328
                 SSO0329 SSO0665
            SCE: YKL192C
            SPO: SPAC11E3.12 SPAC4H3.09 SPBC18E5.10
            ATH: AT4g02580 AT5g08530 AT5g11770 AT5g37510 At1g16700 At1g65290
                 At1g79010 At1g79200 At2g02050 At2g20360 At2g44620
            CEL: C09H10.3 C16A3.4 C18E9.4 C25A1.13 C33A12.1 D2030.4 F16B4.6
                 F22D6.4 F37C12.3 F44G4.2 F53F4.10 F59C6.5 K04G7.4 K09A9.5
                 T10E9.7 T20H4.5 T26A5.3 W10D5.2 Y51H1A.3a Y51H1A.3b Y57G11C.12
                 Y63D3A.7
            DME: CG10320 CG11423 CG11913 CG12079 CG15328 CG15434 CG1970 CG2014
                 CG2286 CG3192 CG3621 CG3683 CG3944 CG5548 CG5703 CG6020 CG6343
                 CG6463 CG6485 CG6914 CG7712 CG8102 CG8844 CG9140 CG9160
                 CG9160_1 CG9172 CG9306 CG9762
            HSA: 4535 4536 4537 4538 4539 4540 4541 4694 4695 4696 4697 4698
                 4700 4701 4702 4704 4705 4706 4707 4708 4709 4710 4711 4712
                 4713 4714 4715 4716 4717 4718 4719 4720 4722 4723 4724 4725
                 4726 4727 4728 4729 4731
DISEASE     MIM: 300078  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1,
                         7.5kD
            MIM: 601677  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
                         (13kD, B13)
DBLINKS     IUBMB Enzyme Nomenclature: 1.6.5.3
            ExPASy - ENZYME nomenclature database: 1.6.5.3
            WIT (What Is There) Metabolic Reconstruction: 1.6.5.3
            BRENDA, the Enzyme Database: 1.6.5.3
///
ENTRY       EC 1.14.13.28
NAME        3,9-Dihydroxypterocarpan 6a-monooxygenase
            3,9-Dihydroxypterocarpan 6a-hydroxylase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
SYSNAME     (6aR,11aR)-3,9-Dihydroxypterocarpan,NADPH:oxygen oxidoreductase
            $ (6a-hydroxylating)
REACTION    (6aR,11aR)-3,9-Dihydroxypterocarpan + NADPH + O2 =
            (6aS,11aS)-3,6a,9-Trihydroxypterocarpan + NADP+ + H2O
SUBSTRATE   (6aR,11aR)-3,9-Dihydroxypterocarpan
            NADPH
            O2
PRODUCT     (6aS,11aS)-3,6a,9-Trihydroxypterocarpan
            NADP+
            H2O
COFACTOR    Heme
COMMENT     Possibly a heme-thiolate protein (P-450).  The product of the
            reaction is the biosynthetic precursor of the phytoalexin
            glyceollin in soybean.
DBLINKS     IUBMB Enzyme Nomenclature: 1.14.13.28
            ExPASy - ENZYME nomenclature database: 1.14.13.28
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.28
            BRENDA, the Enzyme Database: 1.14.13.28
///
ENTRY       EC 2.4.1.68
NAME        Glycoprotein 6-alpha-L-fucosyltransferase
            GDPfucose--glycoprotein fucosyltransferase
CLASS       Transferases
            Glycosyltransferases
            Hexosyltransferases
SYSNAME     GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked
            $ N-acetylglucosamine of N-acetyl-beta-D-glucosaminyl-1,2-alpha-
            $D-mannosyl-1,3-(R1-alpha-1,6)-beta-D-mannosyl-1,4-beta-N-acetyl-
            $D-glucosaminyl-1,4-N-acetyl-D-glucosaminyl)asparagine 6-alpha-L-
            $fucosyltransferase
REACTION    GDP-L-fucose + N4-(N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-
            $mannosyl-1,3-(R1-alpha-1,6)-beta-D-mannosyl-beta-N-acetyl-1,4-
            $D-glucosaminyl-1,4-N-acetyl-D-glucosaminyl)asparagine = GDP +
            N4-(N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-
            $(R1-alpha-1,6)-beta-D-mannosyl-1,4-beta-N-acetyl-D-glucosaminyl-
            $1,4-(alpha-L-fucosyl-1,6)-N-acetyl-D-glucosaminyl)asparagine
SUBSTRATE   GDP-L-fucose
            N4-(N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-
            $(R1-alpha-1,6)-beta-D-mannosyl-beta-N-acetyl-1,4-D-glucosaminyl-
            $1,4-N-acetyl-D-glucosaminyl)asparagine
PRODUCT     GDP
            N4-(N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-
            $(R1-alpha-1,6)-beta-D-mannosyl-1,4-beta-N-acetyl-D-glucosaminyl-
            $1,4-(alpha-L-fucosyl-1,6)-N-acetyl-D-glucosaminyl)asparagine
PATHWAY     PATH: MAP00510  Glycoprotein biosynthesis
DBLINKS     IUBMB Enzyme Nomenclature: 2.4.1.68
            ExPASy - ENZYME nomenclature database: 2.4.1.68
            WIT (What Is There) Metabolic Reconstruction: 2.4.1.68
            BRENDA, the Enzyme Database: 2.4.1.68
///
ENTRY       EC 3.1.1.6
NAME        Acetylesterase
            C-esterase (in animal tissues)
CLASS       Hydrolases
            Acting on ester bonds
            Carboxylic ester hydrolases
SYSNAME     Acetic-ester acetylhydrolase
REACTION    an Acetic ester + H2O = an Alcohol + Acetate
SUBSTRATE   Acetic ester
            H2O
PRODUCT     Alcohol
            Acetate
GENES       MMU: 95428
STRUCTURES  PDB: 1BS9  1G66  2AXE  
DBLINKS     IUBMB Enzyme Nomenclature: 3.1.1.6
            ExPASy - ENZYME nomenclature database: 3.1.1.6
            WIT (What Is There) Metabolic Reconstruction: 3.1.1.6
            UM-BBD (Biocatalysis/Biodegradation Database): 3.1.1.6
            BRENDA, the Enzyme Database: 3.1.1.6
            SCOP (Structural Classification of Proteins): 3.1.1.6
///
ENTRY       EC 2.7.2.1
NAME        Acetate kinase
            Acetokinase
CLASS       Transferases
            Transferring phosphorus-containing groups
            Phosphotransferases with a carboxyl group as acceptor
SYSNAME     ATP:acetate phosphotransferase
REACTION    ATP + Acetate = ADP + Acetyl phosphate
SUBSTRATE   ATP
            Acetate
            Propanoate
PRODUCT     ADP
            Acetyl phosphate
            Propanoyl phosphate
COMMENT     Propanoate also acts as acceptor, but more slowly.
PATHWAY     PATH: MAP00620  Pyruvate metabolism
            PATH: MAP00640  Propanoate metabolism
GENES       ECO: ECOLI_2245
            HIN: HI1204
            BSU: ackA
            MGE: MG357
            MPN: G12_orf390
            SYN: sll1299
DBLINKS     University of Geneva ENZYME DATA BANK: 2.7.2.1
            WIT (What Is There) Metabolic Reconstruction: 2.7.2.1
            PIR: B49338  B49935  E64239  KIECAA
///


Testing Bio.KEGG.Enzyme on enzyme.irregular


ENTRY       EC 1.14.18.1
NAME        Monophenol monooxygenase
            Tyrosinase
            Phenolase
            Monophenol oxidase
            Cresolase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With another compound as one donor, and incorporation of one atom
            of oxygen
SYSNAME     Monophenol,L-dopa:oxygen oxidoreductase
REACTION    L-Tyrosine + L-Dopa + O2 = L-Dopa + Dopaquinone + H2O
SUBSTRATE   L-Tyrosine
            L-Dopa
            Benzenediol
            O2
PRODUCT     L-Dopa
            Dopaquinone
            H2O
COFACTOR    Copper
COMMENT     A group of copper proteins that also catalyse the reaction of
            EC 1.10.3.1, if only benzenediols are available as substrate.
            (EC 1.10.3.1 Catechol oxidase)
PATHWAY     PATH: MAP00350  Tyrosine metabolism
            PATH: MAP00740  Riboflavin metabolism
            PATH: MAP00940  Flavonoids, stilbene and lignin biosynthesis
            PATH: MAP00950  Alkaloid biosynthesis I
GENES       DME: CG5779
            MMU: 94856 98880
            HSA: 7299
DISEASE     MIM: 203100  Tyrosinase
DBLINKS     IUBMB Enzyme Nomenclature: 1.14.18.1
            ExPASy - ENZYME nomenclature database: 1.14.18.1
            WIT (What Is There) Metabolic Reconstruction: 1.14.18.1
            BRENDA, the Enzyme Database: 1.14.18.1
///
ENTRY       EC 3.4.21.50
NAME        Lysyl endopeptidase
            Achromobacter proteinase I
            Endoproteinase Lys-C
            Ps-1
CLASS       Hydrolases
            Acting on peptide bonds (peptidases)
            Serine endopeptidases
REACTION    Preferential cleavage: Lys+, including -Lys-|-Pro-
SUBSTRATE   Protein
            Peptide
            H2O
PRODUCT     Protein
            Peptide
COMMENT     A chymotrypsin homologue isolated from Achromobacter lyticus.
            Enzymes with similar specificity are produced by Lysobacter
            enzymogenes (Endoproteinase Lys-C) and Pseudomonas aeruginosa
            (Ps-1).
            Also hydrolyses lysine amides and esters.
GENES       MJA: MJ1468
            MTH: MTH995
STRUCTURES  PDB: 1ARC  1ARB  
DBLINKS     IUBMB Enzyme Nomenclature: 3.4.21.50
            ExPASy - ENZYME nomenclature database: 3.4.21.50
            WIT (What Is There) Metabolic Reconstruction: 3.4.21.50
            BRENDA, the Enzyme Database: 3.4.21.50
            SCOP (Structural Classification of Proteins): 3.4.21.50
///


Testing Bio.KEGG.Enzyme on enzyme.new


ENTRY       EC 6.2.1.25
NAME        benzoate---CoA ligase
            benzoate---coenzyme A ligase
            benzoyl-coenzyme A synthetase
            benzoyl CoA synthetase (AMP forming)
CLASS       Ligases;
            Forming carbon-sulfur bonds;
            Acid-thiol ligases
SYSNAME     benzoate:CoA ligase (AMP-forming)
REACTION    ATP + benzoate + CoA = AMP + diphosphate + benzoyl-CoA [RN:R01422]
SUBSTRATE   ATP [CPD:C00002]
            benzoate [CPD:C00180]
            CoA [CPD:C00010]
PRODUCT     AMP [CPD:C00020]
            diphosphate [CPD:C00013]
            benzoyl-CoA [CPD:C00512]
COMMENT     Also acts on 2-, 3- and 4-fluorobenzoate, but only very slowly on
            the corresponding chlorobenzoates.
PATHWAY     PATH: ec00362  Benzoate degradation
            PATH: ec00627  Aminobenzoate degradation
            PATH: ec01100  Metabolic pathways
            PATH: ec01120  Microbial metabolism in diverse environments
GENES       REU: Reut_A1327
            REH: H16_A1412 H16_B1918
            RME: Rmet_1224
            CTI: RALTA_A1325 RALTA_B1617
            CNC: CNE_1c14400 CNE_2c18780
            BXE: Bxe_A1419 Bxe_C0896
            BPH: Bphy_1543
            BPY: Bphyt_2700
            BGL: bglu_2g11460
            BUG: BC1001_2395
            BGE: BC1002_1980
            BGF: BC1003_1063
            BRH: RBRH_00494
            BPT: Bpet3574
            AXY: AXYL_05035
            AKA: TKWG_07570
            RFR: Rfer_0216
            POL: Bpro_1624 Bpro_2983
            PNA: Pnap_2948
            VEI: Veis_0730
            DAC: Daci_0076
            DEL: DelCs14_0077
            VAP: Vapar_0089
            VPE: Varpa_0102
            CTT: CtCNB1_0097
            RTA: Rta_22340
            LCH: Lcho_3655
            EBA: ebA2757 ebA5301
            AZO: azo3052
            TMZ: Tmz1t_3136
            GME: Gmet_2143
            GLO: Glov_2397
            GEO: Geob_0200
            GEM: GM21_2825
            DMA: DMR_19390
            DAS: Daes_3238
            DPR: Despr_3172
            DTI: Desti_5323
            BJA: blr1077
            BRA: BRADO6791
            BBT: BBta_0747 BBta_6637
            RPA: RPA0661 RPA0669
            RPB: RPB_4656
            RPC: RPC_1016 RPC_1025
            RPD: RPD_1526 RPD_1534
            RPE: RPE_0592 RPE_0604
            RPT: Rpal_0728 Rpal_0736
            RPX: Rpdx1_4117 Rpdx1_4125
            RVA: Rvan_0044
            SIL: SPO3697
            JAN: Jann_0669
            SWI: Swit_0829
            RPM: RSPPHO_01133
            MAG: amb2869
            GYC: GYMC61_2828
            GYA: GYMC52_1957
            GCT: GC56T3_1519
            SCB: SCAB_8391
            SCT: SCAT_5491
            SCY: SCATT_54890
            BSD: BLASA_2555
            AMD: AMED_8609
            AMN: RAM_35745 RAM_44185
            AMM: AMES_6861 AMES_8478
            PDX: Psed_1491
DBLINKS     ExplorEnz - The Enzyme Database: 6.2.1.25
            IUBMB Enzyme Nomenclature: 6.2.1.25
            ExPASy - ENZYME nomenclature database: 6.2.1.25
            UM-BBD (Biocatalysis/Biodegradation Database): 6.2.1.25
            BRENDA, the Enzyme Database: 6.2.1.25
            CAS: 95329-17-2
///


Testing Bio.KEGG.Compound on compound.sample


ENTRY       C00023
NAME        Iron
            Fe2+
            Fe(II)
            Fe3+
            Fe(III)
FORMULA     Fe
PATHWAY     PATH: MAP00860  Porphyrin and chlorophyll metabolism
ENZYME      1.1.3.22 (C)    1.1.3.26 (C)    1.2.1.43 (C)    1.2.3.10 (C)   
            1.2.99.2 (C)    1.3.1.31 (C)    1.3.1.53 (C)    1.3.5.1 (C)    
            1.3.99.1 (C)    1.3.99.11 (C)   1.4.1.13 (C)    1.4.7.1 (C)    
            1.5.1.13 (C)    1.5.3.11 (C)    1.5.5.1 (C)     1.6.5.3 (C)    
            1.6.6.4 (C)     1.6.99.3 (C)    1.6.99.13 (R)   1.6.99.13 (R)  
            1.7.7.1 (C)     1.7.7.2 (C)     1.7.99.4 (C)    1.8.1.2 (C)    
            1.8.7.1 (C)     1.8.99.1 (C)    1.8.99.2 (C)    1.8.99.3 (C)   
            1.9.99.1 (R)    1.9.99.1 (R)    1.9.99.1 (C)    1.12.1.2 (C)   
            1.12.2.1 (C)    1.12.99.1 (C)   1.13.11.1 (C)   1.13.11.2 (C)  
            1.13.11.3 (C)   1.13.11.4 (C)   1.13.11.5 (C)   1.13.11.6 (C)  
            1.13.11.8 (C)   1.13.11.9 (C)   1.13.11.10 (C)  1.13.11.12 (C) 
            1.13.11.13 (C)  1.13.11.15 (C)  1.13.11.16 (C)  1.13.11.18 (C) 
            1.13.11.19 (C)  1.13.11.20 (C)  1.13.11.21 (C)  1.13.11.25 (C) 
            1.13.11.32 (C)  1.13.11.36 (C)  1.13.11.37 (C)  1.13.11.38 (C) 
            1.13.11.43 (C)  1.13.99.1 (C)   1.14.11.1 (C)   1.14.11.2 (C)  
            1.14.11.3 (C)   1.14.11.4 (C)   1.14.11.6 (C)   1.14.11.7 (C)  
            1.14.11.8 (C)   1.14.11.9 (C)   1.14.11.10 (C)  1.14.11.11 (C) 
            1.14.11.12 (C)  1.14.11.14 (C)  1.14.11.15 (C)  1.14.11.16 (C) 
            1.14.11.17 (C)  1.14.12.1 (C)   1.14.12.3 (C)   1.14.12.7 (C)  
            1.14.12.8 (C)   1.14.12.9 (C)   1.14.12.10 (C)  1.14.12.12 (C) 
            1.14.12.13 (C)  1.14.13.12 (C)  1.14.13.25 (C)  1.14.13.61 (C) 
            1.14.15.2 (C)   1.14.16.1 (C)   1.14.16.2 (C)   1.14.16.3 (C)  
            1.14.16.4 (C)   1.14.16.6 (C)   1.14.99.3 (R)   1.14.99.5 (C)  
            1.14.99.18 (C)  1.14.99.25 (C)  1.15.1.1 (C)    1.16.3.1 (R)   
            1.16.3.1 (R)    1.17.4.1 (C)    1.17.4.2 (C)    1.18.1.1 (C)   
            1.18.99.1 (C)   3.5.1.56 (C)    3.5.4.8 (C)     3.6.3.30 (R)   
            4.2.1.3 (C)     4.2.1.32 (C)    4.2.1.35 (C)    4.2.1.81 (C)   
            4.2.1.84 (C)    4.2.1.85 (C)    4.99.1.1 (R)    
DBLINKS     CAS: 7439-89-6
            PROMISE: FEFEMAIN RNRR2 FERROXIDASE FERRITIN RUBRERYTHRIN
                     HAEMERYTHRIN PAP HAEMMAIN CATALASE CYTOCHROMES COX CYTB
                     BACFERRITIN CYTBHBL CYTB5 SULFOXIDASE CYTB562 CYTC CYTCI
                     CYTCII CYTCIII CYTCIV CYTC1 CYTC554 CYTCD1 CYTF HAO CYTBC1
                     GLOBINS PEROXIDASES ANPEROXIDASE FPBPEROXIDASE
                     HAEM_THIOLATE HAEMCPO NOS P450 NITROPHORIN SIROHAEM
                     FESMAIN FECYS4 DESULFOREDOXIN DFX RUBREDOXIN 2FE2S
                     ADRENODOXIN PLANTFRDX FEHASE XANTOXIDASE RIESKE ARHD 4FE4S
                     ACONITASE AOR BACFRDX DMSOR ENDONUCLEASE3 GPATASE HIPIP
                     NITROGENASE1 NITROGENASE2 NIFE PRISMANE TMADH FEMAIN AAAOH
                     EARCD FESOD IARCD IPNS LIPOXYGENASE NHASE PRCPB
///
ENTRY       C00017
NAME        Protein
PATHWAY     PATH: MAP00251  Glutamate metabolism
            PATH: MAP00252  Alanine and aspartate metabolism
            PATH: MAP00290  Valine, leucine and isoleucine biosynthesis
            PATH: MAP00330  Arginine and proline metabolism
            PATH: MAP00450  Selenoamino acid metabolism
ENZYME      2.3.2.6 (R)     2.3.2.8 (R)     2.4.1.94 (R)    2.4.1.109 (R)  
            2.4.1.112 (R)   2.4.1.113 (R)   2.4.2.33 (R)    2.7.1.37 (R)   
            2.7.1.123 (R)   3.1.2.22 (R)    3.1.3.16 (R)    3.4.11.10 (R)  
            3.4.11.10 (R)   3.4.19.3 (R)    3.4.19.3 (R)    3.4.21.10 (R)  
            3.4.21.10 (R)   3.4.21.20 (R)   3.4.21.32 (R)   3.4.21.32 (R)  
            3.4.21.36 (R)   3.4.21.36 (R)   3.4.21.37 (R)   3.4.21.37 (R)  
            3.4.21.50 (R)   3.4.21.50 (R)   3.4.21.53 (R)   3.4.21.53 (R)  
            3.4.21.59 (R)   3.4.21.59 (R)   3.4.21.61 (R)   3.4.21.62 (R)  
            3.4.21.62 (R)   3.4.21.64 (R)   3.4.21.64 (R)   3.4.21.66 (R)  
            3.4.21.66 (R)   3.4.22.1 (R)    3.4.22.1 (R)    3.4.22.2 (R)   
            3.4.22.2 (R)    3.4.22.3 (R)    3.4.22.3 (R)    3.4.22.6 (R)   
            3.4.22.6 (R)    3.4.22.7 (R)    3.4.22.7 (R)    3.4.22.8 (R)   
            3.4.22.8 (R)    3.4.22.10 (R)   3.4.22.10 (R)   3.4.22.14 (R)  
            3.4.22.14 (R)   3.4.22.15 (R)   3.4.22.15 (R)   3.4.22.16 (R)  
            3.4.22.16 (R)   3.4.22.17 (R)   3.4.22.17 (R)   3.4.22.25 (R)  
            3.4.22.25 (R)   3.4.22.27 (R)   3.4.22.27 (R)   3.4.22.28 (R)  
            3.4.22.29 (R)   3.4.22.30 (R)   3.4.22.30 (R)   3.4.22.31 (R)  
            3.4.22.31 (R)   3.4.22.32 (R)   3.4.22.32 (R)   3.4.22.33 (R)  
            3.4.22.33 (R)   3.4.22.34 (R)   3.4.22.34 (R)   3.4.22.35 (R)  
            3.4.22.35 (R)   3.4.23.1 (R)    3.4.23.1 (R)    3.4.23.3 (R)   
            3.4.23.3 (R)    3.4.23.4 (R)    3.4.23.4 (R)    3.4.23.5 (R)   
            3.4.23.5 (R)    3.4.23.12 (R)   3.4.23.12 (R)   3.4.23.16 (R)  
            3.4.23.16 (R)   3.4.23.17 (R)   3.4.23.17 (R)   3.4.23.18 (R)  
            3.4.23.18 (R)   3.4.23.19 (R)   3.4.23.19 (R)   3.4.23.20 (R)  
            3.4.23.20 (R)   3.4.23.21 (R)   3.4.23.21 (R)   3.4.23.22 (R)  
            3.4.23.22 (R)   3.4.23.23 (R)   3.4.23.23 (R)   3.4.23.24 (R)  
            3.4.23.24 (R)   3.4.23.25 (R)   3.4.23.25 (R)   3.4.23.26 (R)  
            3.4.23.26 (R)   3.4.23.27 (R)   3.4.23.27 (R)   3.4.23.28 (R)  
            3.4.23.28 (R)   3.4.23.29 (R)   3.4.23.29 (R)   3.4.23.30 (R)  
            3.4.23.30 (R)   3.4.23.31 (R)   3.4.23.31 (R)   3.4.23.32 (R)  
            3.4.23.32 (R)   3.4.23.33 (R)   3.4.23.33 (R)   3.4.23.34 (R)  
            3.4.23.34 (R)   3.4.24.1 (R)    3.4.24.1 (R)    3.4.24.3 (R)   
            3.4.24.6 (R)    3.4.24.6 (R)    3.4.24.7 (R)    3.4.24.11 (R)  
            3.4.24.11 (R)   3.4.24.12 (R)   3.4.24.12 (R)   3.4.24.15 (R)  
            3.4.24.15 (R)   3.4.24.17 (R)   3.4.24.17 (R)   3.4.24.18 (R)  
            3.4.24.18 (R)   3.4.24.20 (R)   3.4.24.20 (R)   3.4.24.21 (R)  
            3.4.24.21 (R)   3.4.24.22 (R)   3.4.24.22 (R)   3.4.24.23 (R)  
            3.4.24.24 (R)   3.4.24.25 (R)   3.4.24.25 (R)   3.4.24.26 (R)  
            3.4.24.27 (R)   3.4.24.27 (R)   3.4.24.28 (R)   3.4.24.28 (R)  
            3.4.24.29 (R)   3.4.24.29 (R)   3.4.24.30 (R)   3.4.24.30 (R)  
            3.4.24.31 (R)   3.4.24.31 (R)   3.4.24.32 (R)   3.4.24.32 (R)  
            3.4.24.33 (R)   3.4.24.33 (R)   3.4.24.34 (R)   3.4.24.36 (R)  
            3.4.24.36 (R)   3.4.24.37 (R)   3.4.24.37 (R)   3.4.24.38 (R)  
            3.4.24.38 (R)   3.4.24.39 (R)   3.4.24.39 (R)   3.4.24.40 (R)  
            3.4.24.40 (R)   3.4.24.41 (R)   3.4.24.41 (R)   3.4.24.42 (R)  
            3.4.24.42 (R)   3.4.24.43 (R)   3.4.24.43 (R)   3.4.24.44 (R)  
            3.4.24.44 (R)   3.4.24.45 (R)   3.4.24.45 (R)   3.4.24.46 (R)  
            3.4.24.46 (R)   3.4.24.47 (R)   3.4.24.47 (R)   3.4.24.48 (R)  
            3.4.24.48 (R)   3.4.24.49 (R)   3.4.24.49 (R)   3.4.24.50 (R)  
            3.4.24.50 (R)   3.4.24.51 (R)   3.4.24.51 (R)   3.4.24.52 (R)  
            3.4.24.52 (R)   3.4.24.53 (R)   3.4.24.53 (R)   3.4.24.54 (R)  
            3.4.24.54 (R)   3.4.99.43 (R)   3.4.99.43 (R)   3.4.99.46 (R)  
            3.4.99.46 (R)   6.2.1.19 (R)    
///
ENTRY       C00099
NAME        beta-Alanine
            3-aminopropionic acid
            3-Aminopropanoate
FORMULA     C3H7NO2
PATHWAY     PATH: MAP00240  Pyrimidine metabolism
            PATH: MAP00252  Alanine and aspartate metabolism
            PATH: MAP00410  beta-Alanine metabolism
            PATH: MAP00640  Propanoate metabolism
            PATH: MAP00770  Pantothenate and CoA biosynthesis
ENZYME      1.5.1.26 (R)    2.6.1.18 (R)    2.6.1.19 (R)    2.6.1.55 (R)   
            3.4.13.3 (R)    3.4.13.5 (R)    3.4.13.20 (R)   3.5.1.6 (R)    
            3.5.1.21 (R)    3.5.1.22 (R)    3.5.3.17 (R)    4.1.1.11 (R)   
            4.1.1.15 (R)    6.3.2.1 (R)     6.3.2.11 (R)    6.3.2.23 (R)    
DBLINKS     CAS: 107-95-9
///
ENTRY       C00294
NAME        Inosine
FORMULA     C10H12N4O5
PATHWAY     PATH: MAP00230  Purine metabolism
ENZYME      1.1.3.28 (R)    2.7.1.73 (R)    3.2.2.2 (R)     3.5.4.4 (R)    
            3.5.4.17 (R)    
DBLINKS     CAS: 58-63-9
///
ENTRY       C00298
NAME        Trypsin
ENZYME      3.4.21.9 (R)    3.4.23.18 (R)   3.4.23.20 (R)   3.4.23.24 (R)  
            3.4.23.26 (R)   
///
ENTRY       C00348
NAME        Undecaprenyl phosphate
PATHWAY     PATH: MAP00550  Peptideglycan biosynthesis
ENZYME      2.4.1.54 (R)    2.7.1.66 (R)    2.7.8.6 (R)     2.7.8.13 (R)   
            3.6.1.27 (R)    
///
ENTRY       C00349
NAME        2-Methyl-3-oxopropanoate
            3-Oxo-2-methylpropanoate
            Methylmalonate semialdehyde
FORMULA     C4H6O3
ENZYME      1.1.1.31 (R)    1.2.1.27 (R)    2.6.1.22 (R)    2.6.1.40 (R)   
            2.6.1.61 (R)    
///
ENTRY       C01386
NAME        NH2Mec
ENZYME      3.4.22.32 (R)   
///


Testing Bio.KEGG.Compound on compound.irregular


ENTRY       C01454
NAME        Toluate
            p-Toluate
            p-Toluic acid
            4-Methylbenzoic acid
            Toluenecarboxylic acid
            Crithminic acid
FORMULA     C8H8O2
MASS        136.0524
PATHWAY     PATH: map00622  Toluene and xylene degradation
ENZYME      1.2.1.7         1.14.12.-       
DBLINKS     CAS: 99-94-5
            PubChem: 4631
            ChEBI: 36635
            3DMET: B00292
///
ENTRY       C06876
NAME        Nitrosobenzene
FORMULA     C6H5NO
MASS        107.0371
PATHWAY     PATH: map00626  Naphthalene and anthracene degradation
ENZYME      1.6.6.-         
DBLINKS     CAS: 586-96-9
            PubChem: 9093
            3DMET: B01057
///


Testing Bio.KEGG.Map on map00950.rea


(R)-N-Methylcoclaurine + (S)-Coclaurine + NADPH + O2 <=> 2'-Norberbamunine + 2 H2O + NADP
(R)-N-Methylcoclaurine + (S)-N-Methylcoclaurine + NADPH + O2 <=> Berbamunine + 2 H2O + NADP
(R)-Norreticuline + S-Adenosyl-L-methionine <=> (R)-Reticuline + S-Adenosyl-L-homocysteine
(R)-Reticuline + NADPH + O2 <=> 2 H2O + NADP+ + Salutaridine
(S)-3'-Hydroxycoclaurine + S-Adenosyl-L-methionine <=> (S)-Norreticuline + S-Adenosyl-L-homocysteine
(S)-6-O-Methylnorlaudanosoline + S-Adenosyl-L-methionine <=> (S)-Nororientaline + S-Adenosyl-L-homocysteine
(S)-Canadine + 2 O2 <=> Berberine + 2 H2O2
(S)-Cheilanthifoline + NADPH + O2 <=> (S)-Stylopine + 2 H2O + NADP+
(S)-Coclaurine + S-Adenosyl-L-methionine <=> (S)-N-Methylcoclaurine + S-Adenosyl-L-homocysteine
(S)-N-Methylcoclaurine <=> (S)-3'-Hydroxy-N-methylcoclaurine
(S)-Norcoclaurine + S-Adenosyl-L-methionine <=> (S)-Coclaurine + S-Adenosyl-L-homocysteine
(S)-Norlaudanosoline + S-Adenosyl-L-methionine <=> (S)-6-O-Methylnorlaudanosoline + S-Adenosyl-L-homocysteine
(S)-Norreticuline + S-Adenosyl-L-methionine <=> (S)-Reticuline + S-Adenosyl-L-homocysteine
(S)-Reticuline + O2 <=> (S)-Scoulerine + H2O2
(S)-Scoulerine + NADPH + O2 <=> (S)-Cheilanthifoline + 2 H2O + NADP+
(S)-Scoulerine + S-Adenosyl-L-methionine <=> (S)-Tetrahydrocolumbamine + S-Adenosyl-L-homocysteine
(S)-Stylopine + S-Adenosyl-L-methionine <=> (S)-cis-N-methylstylopine
(S)-Tetrahydrocolumbamine + 2 O2 <=> Columbamine + 2 H2O2
(S)-Tetrahydrocolumbamine + NADPH + O2 <=> (S)-Canadine + 2 H2O + NADP+
(S)-Tetrahydrocolumbamine + S-Adenosyl-L-methionine <=> S-Adenosyl-L-homocysteine + Tetrahydropalmatine
(S)-cis-N-methylstylopine <=> Protopine
1,2-Dehydroreticuline + NADPH <=> (R)-Reticuline + NADP+
10-Hydroxydihydrosanguinarine + S-Adenosyl-L-methionine <=> Dihydrochelirubine + S-Adenosyl-L-homocysteine
12-Hydroxydihydrochelirubine + S-Adenosyl-L-methionine <=> Dihydromacarpine + S-Adenosyl-L-homocysteine
2 (R)-N-Methylcoclaurine + NADPH + O2 <=> Guattegaumerine + 2 H2O + NADP
2 Columbamine + O2 <=> 2 Berberine + 2 H2O
2-Oxoglutarate + L-Tyrosine <=> 3-(4-Hydroxyphenyl)pyruvate + L-Glutamate
2-Oxoglutarate + L-Tyrosine <=> 4-Hydroxyphenylpyruvate + L-Glutamate
2-Oxoglutarate + L-Tyrosine <=> 4-Hydroxyphenylpyruvate + L-Glutamate
3'-Hydroxy-N-methyl-(S)-coclaurine + S-Adenosyl-L-methionine <=> (S)-Reticuline + S-Adenosyl-L-homocysteine
3,4-Dihydroxyphenylacetaldehyde + Dopamine <=> (S)-Norlaudanosoline + H2O
4-Hydroxyphenylacetaldehyde + Dopamine <=> (S)-Norcoclaurine + H2O
4-Hydroxyphenylpyruvate <=> 4-Hydroxyphenylacetaldehyde + CO2
6-Hydroxyprotopine <=> Dihydrosanguinarine
7-O-Acetylsalutaridinol <=> Thebaine
Acetyl-CoA + Salutaridinol <=> 7-O-Acetylsalutaridinol + CoA
Codeinone + NADPH <=> Codeine + NADP+
Columbamine + S-Adenosyl-L-methionine <=> Palmatine + S-Adenosyl-L-homocysteine
Dihydrochelirubine + O2 <=> Chelirubine + H2O2
Dihydrochelirubine <=> 12-Hydroxychelirubine
Dihydromacarpine + O2 <=> H2O2 + Macarpine
Dihydrosanguinarine + NADPH + O2 <=> 10-Hydroxydihydrosanguinarine + H2O + NADP+
Dihydrosanguinarine + O2 <=> H2O2 + Sanguinarine
H2O + L-Tyrosine + O2 <=> 4-Hydroxyphenylpyruvate + H2O2 + NH3
L-Tyrosine <=> CO2 + Tyramine
L-Tyrosine <=> CO2 + Tyramine
Morphine + NAD+ <=> Morphinone + NADH
Morphine + NADP+ <=> Morphinone + NADPH
Morphinone <=> Codeine
NADPH + O2 + Protopine <=> 6-Hydroxyprotopine + H2O + NADP+
NADPH + Salutaridine <=> NADP+ + Salutaridinol
Neopinone <=> Codeinone
Oripavine <=> Morphinone
Thebaine <=> Neopinone
Thebaine <=> Oripavine
Tyramine <=> Dopamine
